Pharmacological effects 1. Effect on the cardiovascular system a. Effects on the heart: Experiments have shown that: Rehmanniae extract has a significant effect on the contractile force of the frog heart, and is more pronounced on the debilitating heart, but large doses can cause normal frog heart poisoning, and rats are injected intravenously with ethanol Extracts, water extracts, have a significant inhibitory effect on the heart, slow down or even stop the heartbeat. Therefore, the toxicity of the heart should be paid attention to when using large doses of yellow. b. Effect on blood pressure: Rats were given intraperitoneal injection of Huai water, alcohol, and ether extracts. The results showed that: water extract has significant antihypertensive effect on acute experimental hypertension, while alcohol and ether extracts have no obvious effect on hypertension. The effect is stable to the blood pressure in the cold (room temperature 23°C). Rehmannia extract intravenously in rabbits and dogs can increase blood pressure. When the hind leg is perfused, the medium concentration causes the blood vessels to contract and the high concentration causes the blood vessels to expand. 4. Intravenous alcohol extracts of Huaiqing Rehmannia for anesthetized dogs and rabbits can lower blood pressure. Experiments show that: Liuwei Dihuang Decoction on experimental renal hypertension in rats with significant blood pressure, improve renal function, reduce the mortality rate. 2. Effect on Blood The yellow needle crystals obtained from the ethanol extract of Rehmannia can shorten rabbit clotting time, but the effect of decoction is not obvious. The experiment proved that the decoctions of Rehmannia glutinosa, Rehmannia glutinosa, Rehmannia charcoal and Rehmannia charcoal can significantly shorten the clotting time, and there is no significant difference between them. A study of DIC effects of nine different rehmanniae and rehmannia has shown that one of the Chinese-produced Rehmannia glutinosa has the effect of antithrombin, and the two have the function of activating the fibrinolysis system, and can obviously resist the induction of thrombin and endotoxin. The occurrence of DIC in rats, but no platelet aggregation. Rehmannia has both hemostatic effect and anticoagulant effect, and its mechanism needs further study. The rats were intraperitoneally injected with 100% of the raw land injection, 1 ml per day, for 6 consecutive days, which reduced the platelet damage caused by 60 Co dose, and accelerated the recovery. 3. Effect on Blood Sugar The effect of Rehmannia on blood glucose needs further study. Decoction, infusion or alcohol extract can reduce the normal blood sugar and hyperglycemia caused by epinephrine and chloramine after gavage or injection in rabbits. It has been reported that rabbits subcutaneously injected with 2 g/kg solution of genistein or gavage with 4 g/kg can reduce blood glucose. Injection was more obvious, and blood glucose was reduced to the lowest level 4 hours after administration. Intramuscular injection of dilute alcohol solution 20g can also inhibit and prevent epinephrine induced blood glucose in rabbits. The hypoglycemic effect of single-boiled habitat was significantly higher than that of Pueraria lobata; the hypoglycemic effect of Bawei Dihuang Wan was not stronger than that of Di Huang. It has been reported that Bawei Dihuang Decoction has a reduced effect on alloxan-induced hyperglycemia in rats. It has been reported that yellow water or alcohol extracts only reduce blood glucose in normal rabbits but are not effective for epinephrine-induced hyperglycemia. However, there are also reports to the contrary, the use of yellow alcohol extract, decoction, flooding and other experiments on rabbits, did not observe the hypoglycemic effect of Rehmannia. 4. The role of the central nervous system Rehmannia has a clear sedative effect, its role may be in the cerebral cortex. Its water extract inhibits the mice's autonomic activity and enhances the hypnotic effects of subthreshold hypnotic doses of pentobarbital sodium and thiopental, and it also counteracts the excitatory effects of sodium sulphate, but it is not effective against nitric acid. Ning and pentylenetetrazole caused by convulsions. The sedative effect of Rehmannia helps ease the symptoms of hypertensive patients and significantly improves insomnia caused by hypertensive patients with an effective rate of 94%. Some people think that the sedative component of Rehmannia glutinosa is mainly water-soluble, oral yellow decoction extract, alcohol infusion or intraperitoneal injection of 10g/kg can all produce a synergistic effect on the hypnotic effect of pentobarbital sodium. 5. Anti-inflammation and anti-allergic effects of yellow decoction to gavage has a clear antagonistic effect on formaldehyde-induced arthritis and egg white arthritis in rats and can inhibit granuloma and histamine-induced capillary permeability caused by subcutaneous injection of turpentine oil. Increased sex. Radix Rehmanniae extract has an inhibitory effect on increased histamine-induced vascular permeability and acetic acid-induced peritonitis in mice. It also has anti-inflammatory effects on acute inflammation caused by egg white, while alcohol and ether extracts of Rehmannia do not have anti-inflammatory effects. . It has been reported that dry yellow water extract can significantly increase T lymphocytes in peripheral blood, and dry retinol extract can significantly promote anti-SRPC antibody-hemolysin production and reduce peripheral blood T lymphocytes. Rehmannia glutinosa extract has no This effect. 6. Anti-fungal yellow water inoculants have inhibitory effects on the growth of various fungi such as S. bracteatum, G. globularis, G. fimbriformis, and O. anguilla. 7. Endocrine effects of Rehmannia on the inhibition of dexamethasone on the pituitary-adrenocortical system, and can promote the synthesis of adrenocorticotropic hormone. Clinical observation found that the combination of rehmannia and glucocorticoids can reduce the side effects of yin deficiency and impotence caused by hormones. The combination of habitat and dexamethasone can increase the concentration of corticosterone in rabbits, but pathological observations show no obvious changes in morphology of the pituitary and adrenal cortex in rabbits, suggesting that the habitat can reduce the pituitary gland of rabbits by glucocorticoids. - Effects of adrenocortical system function and morphology. Animal experiments show that: Rehmannia can counteract the continuous decrease in plasma corticosterone concentration after dexamethasone administration and prevent adrenal cortical atrophy. Rehmannia decoction gavage can significantly reduce the adrenal vitamin C content in rats. 8. Anti-tumor effects of Liuwei Dihuang Decoction can significantly antagonize the role of N-nitrosine ethyl ester in inducing mouse pro-lump squamous cell carcinoma (human esophageal cancer). It is generally believed that the anti-tumor effect of Rehmannia root is related to the increase of immune function. Rehmannia has the function of promoting the transformation of lymphoblasts in the body, increasing the number of T lymphocytes, and can enhance the phagocytic function of the reticuloendothelial system, especially for those with low immune function. more obvious. 9. Other effects have been reported after an intravenous infusion of Dioscorea extract in anesthetized dogs, the amount of urine per unit time has increased, the diuretic principle may be related to the role of vasomotion and dilation of blood vessels; but there are also reports, Dioscorea extract and alcohol extract The diuretic effect on rats has not been confirmed. The P10 two-color display module all uses the JX5020 driver chip from Taiwan Macroaccumulation. The LEDs of each branch are correspondingly driven by an IC pin. One IC pin drives one LED. We use static cross-current The driving method ensures that the current of each IC can be guaranteed, and the normal guarantee will not cause the entire module to heat up due to the different scanning methods, which will cause damage to the IC, and the brightness of the LED will also be similar to the static cross current. The static cross-current drive ensures the stability of the entire screen. Led Display Outdoor,Taxi Top Led Display,Full Color Led Display,Traffic Led Display Shenzhen Wide Way Optoelectronics Co., Ltd. , https://www.wdmtrafficlight.com
When all the LED display modules are tested, paste QC, pass, and then perform the first semi-finished product test aging. The longer the aging time, the better, let him exceed 24 hours as much as possible, and then we will display the display module Put on the bottom shell, ready to start pouring.
The glue is filled with a fully automatic glue filling machine. After the ab component glue is combined, the filling is carried out according to the ratio of 10:1. It is better not to lower or increase the ratio. The ratio of 10:1 is just right. , It can be surface-dried in about two hours, and it will dry out in about 4-6 hours. Such glue will have a good guarantee for long-term use.
After the module is filled with glue, place the module on a horizontal plane, and test with a level meter, and then try to make each module as flat as possible, complete the 4 corners of the horizontal position on the same level, the choice of AB glue It is also very important. The AB glue choice must use more than 40 yuan per kilogram of glue. Its adhesion and durability will be very good. It cannot be filled with shoddy glue. It will crack after a long time. The screen will leak. Then put all the display modules in their masks and arrange them to start packaging.
The pharmacological effects of Rehmannia