TID: Tobacco smoke can promote bacteria to become more active

Release date: 2016-06-02

The mouth is the "dirty" part of the body, which "lives" millions of bacteria, and smoking may not only increase the colonization capacity of Porphyromonas gingivalis in the mouth, but also help the bacteria Protect against the body's immune system.

Recently, a study published in the international magazine Tobacco Induced Diseases , researchers from the University of Louisville School of Dentistry through research revealed how smoking causes oral bacteria to colonize and colonize, the researchers pointed out that smoking smoke contains Thousands of compounds, and this smoke is an environmental stress factor that promotes bacterial reproduction and immune invasion.

Researcher Dr. David A. Scott said smoking smog and its components promote the formation of biofilms of a variety of bacteria, including Staphylococcus aureus, Streptococcus mutans, Klebsiella pneumoniae and Aluminoxybacteria. Biofilms are composed of many microbial communities, which often form complex, interacting, and coexisting bacterial multi-layer structures, and bacteria often form biofilms in teeth, artificial heart valves, and respiratory tracts.

Once the pathogen itself forms a biofilm, it is difficult for the body to remove it. At the same time, the biofilm also gives the bacteria a protective layer against the host's immune system. The bacteria that produce the biofilm are resistant to many antibiotics. The researchers said that biofilms can transfer genetic material between different bacterial populations, and at the same time promote the spread of virulence factors, thereby promoting the spread of infections.

The most common type of biofilm is plaque, plaque can cause gingivitis, and gingivitis is present in almost universal populations, and plaque can also cause chronic periodontitis in patients; Bacterial biofilms formed on the surface of the heart valve can cause heart-related infections in patients and trigger a series of subsequent health problems. Researcher Scott said that we have been studying to explain the molecular mechanisms involved in the interaction between bacterial populations that form biofilms and related diseases, and many studies have investigated the biofilm formation mechanisms of single bacteria, and scientists have Intensive research has been conducted to develop new therapies that are effective against biofilm-induced diseases.

According to US CDC data, the number of adults smoking in Kentucky has risen to the second place. Later researchers need more in-depth research to clarify why smoking promotes bacteria becoming more resistant, and researchers It is hoped that special effects will be developed that can effectively kill or inhibit the growth of bacteria.

Source: Bio Valley

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