Zika virus causes damage to the testicular volume of mice November 07, 2016 Source: Bio Valley Most studies on Zika Virus have found that the effects of Zika virus infection are mainly concentrated on pregnant women and birth defects. But in mice, new research has found that Zika virus has severely damaged the male reproductive system in mice, raising serious concerns about the threats that human males may be exposed to. Researchers at the University of Washington School of Medicine reported on the damage of the Zika virus to the reproductive system of male mice through a research article in Nature. Studies have found that Zika virus can stay in the semen of infected people for several months. Therefore, the US Centers for Disease Control and Prevention recommends that individuals who have been to a prevalent place in Zika should insist on using condoms for six months, regardless of whether they have had Zika virus infection. Previous studies have not published the virus for human health problems in humans. To understand how Zika virus affects men, the researchers injected the virus into male mice. A week later, the virus had migrated to the testes and an inflammatory response had begun to appear under the microscope. After two weeks, the testicular volume of the male mice was significantly reduced, the internal structure was flattened, and many cells died or died. Three weeks later, the testes of the mice had shrunk to one-tenth of the normal size and the internal structure of the testes was completely destroyed. By continuously monitoring the mice, the testis of the male mice did not completely heal after six weeks, although the virus had disappeared from the bloodstream. The testes normally produce sperm and testosterone, and when the testes of the mice continue to damage, their sperm production and testosterone levels drop dramatically. Six weeks after infection, the number of active sperm decreased tenfold and testosterone levels decreased by a similar multiple. When healthy female mice were mated with infected and non-infected male mice, respectively, the proportion of pregnant females who were mated with infected males was four times lower. The authors point out that although their research is aimed at mice, it should be reminded that we do not know whether Zika virus has the same effect on human males. At least, the study does show that male mice may be infected after Zika infection. Faced with low testosterone levels and a small number of sperm, which in turn affects fertility. If humans also have changes in testicular volume and structure, or even changes in hormone levels, the impact of the virus on human reproductive health will be quite serious, but more research is needed to support this conclusion. Viruses and bacteria are everywhere. Preventing them in advance is the best way to reduce the risk of infection. Wearing a mask and washing hands frequently are crucial. The new type of coronavirus has the characteristics of contact transmission, and the fact that the virus exists on the doorknob of patients with pneumonia has also shown the necessity of paying attention to hand hygiene and wearing disposable protective gloves.
Whether it is going out to purchase daily necessities or buying through online platforms, it is inevitable to come into contact with "foreign" items, such as supermarket shopping carts, packaging bags, express packaging boxes, etc., and more things need to be touched after resuming work, such as It is inevitable to take public transportation, elevators, etc., these places may have been touched by patients or suspected patients. Wearing disposable protective gloves is an effective means to reduce the risk of infection when there is no condition to wash your hands at any time.
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Zika virus causes damage to the testicular volume of mice