On January 4th, Washington time, Counsyl, Illuminansyl, Progenity, Natera and Laboratory corporation of America's speciality lab Intergrated Genetics announced the establishment of the Prenatal Screening Alliance (CAPS). According to reports, CAPS will work together to better achieve non-invasive prenatal screening through cfDNA-based non-invasive prenatal testing (NIPT). Raise public awareness of the value of cfDNA-based NIPT and provide the highest standards and quality of service. At the same time, CAPS will also work to promote the development of relevant legislation and medical insurance coverage to achieve a personalized patient care experience.

1. Illumina

Among the members of the alliance, the most concerned is Illumina. In the early years, Illumina has been playing an upstream role in the industry chain, providing sequencing equipment and chips for sequencing services companies. In 2007, it acquired the gene sequencing company Solexa for US$600 million and entered the mid-stream of sequencing services. In 2013, we acquired Verinata Health and officially laid out the non-invasive prenatal diagnosis market. The cost of NGS testing has been greatly reduced, and gene sequencing has entered the general population. Illumina has played an important role, and the company has taken the lead in the global gene sequencing market. In the CAPS alliance, Illumina will also have a higher status.

2. Natera

Natera is a diagnostic sequencing company that provides non-invasive prenatal testing, as well as previous reports on arterial networks. Natera's core technology is multi-variable detection technology and DNA separation technology, both of which have extremely high sensitivity, requiring only one drop of blood sample. Not only is non-invasive prenatal testing, Natera's technology is also very promising in the field of tumor detection, which can reduce the false negative rate of clinical testing. At the same time, Natera insists on the feasibility and low-cost principle. The company uses non-invasive detection technology to conduct large-scale inspections in large laboratories, which can be tested at a lower cost.

Not only that, Natera's test content is also a highlight, in addition to the mainstream Down syndrome test, it can also detect microdeletions in the fetus, just a drop of blood. Natera's leaders are also very business-minded, not only establishing their own enjoyment network in the United States, but also developing international markets through cooperation with a number of foreign laboratories. Previously, Vice President Mike Bruce also said that he is very optimistic about the Chinese market.

Whether it's core technology or business model, Natera is a strong company. Despite the growing competition in the non-invasive pre-testing market in 2013, Natera did not prevent Natera from achieving good results. In 2013, Natera's cumulative sales reached US$15 million, and it is expected to reach 220 million in 2016. In 2015, the number of people who have been sequenced has reached 310,000. Natera ranks fourth in the prenatal genetic testing market in the United States and is arguably the industry leader.

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