Spanish scientists want to replace the cornea within 5 years

Release date: 2017-08-21

Recently, a team from the Spanish Biomedical Research Institute announced plans to use 3D bioprinting to create alternative corneas. The Institute is located at the La Paz Hospital in Madrid and will create these 3D printed corneas within 5 years. This should have a positive impact on the lives of countless patients.

The goal of this research team is to develop techniques to produce biomimetic human corneal stroma to completely remove the need to donate the cornea. At that time, the doctor will be able to create a custom new 3D printed cornea within 5 days.

This groundbreaking project was funded by the Spanish Innovation and Prospective Health Foundation (Fipse) under the framework of the international Idea2 global project developed by MIT. If successful, millions of people may return to sight.

Currently, the research team is exploring a variety of different options. Basically, they will synthesize a polymeric collagen extracellular matrix that mimics the human cornea, and then print the stem cells 3D into the matrix to create a biokerat. The 3D printing system is ready, and now the team is working hard to get the right nanotechnology to synthesize the collagen matrix needed. To ensure corneal transparency, researchers need to print parallel collagen fibers at specific distances.

The stem cells printed into the matrix are taken from the patient's adipose tissue, which means that the 3D printed cornea will match the existing tissue in the eye to ensure that no rejection occurs.

The research team is now working with experts from MIT and Harvard University to develop a “very interactive” project that will continue until the end of the year.

(Compiled from 3ders.org)

Source: Tiangongshe

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