1. New concept of foreign pharmaceutical packaging design

Foreign drug packaging places great emphasis on child safety (Baby Ssfe), so in the design of drugs, it is often considered whether the design of the packaging will have an impact on the safety of children. Recently, a company developed a medicine box called "Faller". The box is opened by the die-cut line on the box. It takes a certain amount of force to open the tray. This way of opening is very easy for adults. However, it is very difficult for children, thus effectively avoiding children's mis-opening and eating. Since the package is opened once, it is difficult to restore, so it plays a role of anti-theft to a certain extent, and truly integrates protection and anti-theft.

In addition, foreign new wallet blister packaging reflects a more humane focus. For patients with heart disease who need to take regular medication for a long time, this type of packaging is very suitable, because the chip can be added to the box, the chip is designed with a certain program, when the patient forgets to take the medicine, the chip will automatically alarm The humming sound reminds the patient to take medicine.
Because the anti-moisture, moisture-proof and light-proof performance of aluminum-plastic blister packaging are not as good as that of double-aluminum and aluminum-plastic aluminum packaging, the demand for double-aluminum and aluminum-plastic aluminum packaging is on the rise.
In terms of anti-counterfeiting, in addition to the common anti-counterfeiting technology used in packaging boxes and manuals in China, many foreign medicines have been used for anti-counterfeiting on the outer packaging cartons, brochures, and blister-wrapped aluminum foil.
In addition to carton packs and blister packs, there are many new forms of packaging, such as plastic bags with round sponges on one end, paper-like packaging that looks like a vial.

2, suitable for blister packaging of patients with initial use

A foreign company, Zui, recently designed a blister pack for an initial patient for an important customer. The package is completed on a high-speed line, a blister that holds both 10 mg and 20 mg of product, and comes with a patient information booklet and inserts.

3, saving sheet blister packaging machine

Recently, the high-efficiency blister packaging equipment has been innovated. Since the speed of the PS plate and the aluminum-plastic heat sealing is fast, the time is shortened, and the degree of cooling of the PS plate is small, solving the problem that the edge of the bubble and the edge of the cover are asymmetrical. At the same time, this equipment adopts servo drive, which makes the precision of the machine very good. There is no gap between the medicine board and the medicine board, which can save the enterprise 10%~15% of the board.

4, injection bottle blister forming machine

The appearance of an injection bottle blister forming machine enriches the packaging form of the injection bottle and makes the packaging form more beautiful. The equipment package is formed and heat sealed on the same roller, and two different types of injection bottles can be packaged at the same time (the diameter of the injection bottle is 28 mm). In addition, since the injection bottle does not have the problem of moisture resistance, in order to save the packaging cost, it is also possible to use a special paper instead of the aluminum foil and the PVC seal.

5, the blister packaging machine that automatically fills the defective products

A blister packaging machine designed by a German company uses a servo motor to control each station, so that there is no error accumulation, which greatly improves the mechanical running accuracy and saves packaging materials. Its randomly controlled online sample and unique feeding bin design can detect the quality of the product at any time. Once the damaged or empty foamed product is removed, the feeding bin will automatically fall to the qualified product.

6, blister packaging machine to save energy
An aluminum/aluminum blister packaging machine from an Italian company uses a composite aluminum material to form a blister at room temperature and cold forming, which can effectively reduce energy consumption.
7. Blister packaging machine for medium production

The SRS series semi-automatic rotary blister packaging machine is a new type of equipment specially designed for medium production. This machine uses DuPont's Tyver, foil and other heat-sealable lidstock for conventional card blister, front blister, and half-clamshell styles. The SRS series has three stations, six stations and eight stations. In addition, the machine is designed to include an optional automatic card feed system and automatic package removal system.

8. Packing machine with 600 blister packs per minute
A German company uses BP series equipment, with advanced servo performance, box design and positive migration system as the key technology, with flexibility, high efficiency and easy operation.

The traditional design uses a main servo to control other servo drives. This device allows the servo drive to adjust individual processing times without affecting other stations. In addition, the ELAU PacDrive automatic system used in this device can perform more complicated control methods. The box design of the device separates the machine structure from the drive, avoiding the generation of particles and dust, and the work surface has a flat surface that is easy to clean and avoids possible blockages during operation.

The device is quickly adjusted and requires no tools to be configured and replaced via the operator panel. The equipment is divided into single and double channels, which can complete the blister molding with a depth of 12mm and the production speed is up to 600 blister/minute.

9, visually guided robot packaging equipment

The APS robot TigerPak system designed by an automation company can pack at 80 blister strips per minute. The robot is visually guided and the blister strips are placed in any orientation (eg face up or upside down) and the robot picks up the APS custom device and places it in the prepared tray. The system also verifies the picking and placement of each product to prove correct and accurate cart count. This device is suitable for a wide range of blister sizes and can be converted without tools.

10. Demand for multi-row pouch packaging machines is growing rapidly

Many granule drugs are packaged in bags. In recent years, the output of granules in China has grown rapidly. In 2003 alone, it exceeded 6.05 billion bales, an increase of 23% over 2002. As these drugs are in short supply in the market, this means that pharmaceutical companies need higher production speeds. Therefore, high-speed multi-row pouch packaging machines have emerged, with the advantages of higher production speed, lower personnel cost and packaging material cost, and single-row pouch packaging machines, which have a single column with lower production speed. The trend of small bag packaging machine.

11. Cartoning machine with suction cup and unique open box

The cartoning machine is an indispensable part of the blister packaging linkage production line. The domestic cartoning machine generally opens the carton by means of card pushing, so the speed of the cartoning machine has a great relationship with the quality of the paper. If the paper has poor stiffness and the material of the paper is poor, it may cause damage. Open, resulting in downtime. A foreign company has developed a cartoning machine with a suction cup and a unique unpacking device. It uses a suction cup, and has a suction cup on the top and side of the carton to open the carton by suction, thereby reducing the paper requirements of the device. . At the same time, in order to ensure the opening rate of the equipment, the fork hand open box device is specially designed, which makes the replacement of the mold convenient and rapid, thereby avoiding the possibility of downtime due to unsuccessful opening of the box, saving the packaging material and ensuring the production speed. Compared with the higher speed cartoning machine, it has a higher cost performance.

12, drug testing is getting more and more attention

In recent years, the safety of pharmaceutical packaging has been placed in a prominent position. Many medical equipment suppliers have paid special attention to testing equipment: photoelectric detection systems, camera monitoring systems, weighing detection equipment, etc. are all blistered on the linkage line. For example, many blister packaging equipment is equipped with an image detecting device, which can detect the color and size of the medicine before the medicine is filled. When other drugs or damaged drugs are detected, the testing device remembers the location of the drugs and removes them after the zui. There are also testing equipment for products such as vials, which can detect foreign objects, metals, liquid surfaces, damage, etc., and are easy to operate and have high accuracy.

Key Intermediates

Intermediate – Intermediate: A material produced during a drug substance processing step that must undergo further molecular modification or refinement to become a drug substance. Intermediates may or may not be isolated. Intermediates are the key products of the previous process of making APIs, which are different in structure from APIs.