The pharmacological effects of earthworms

Pharmacological effects

Aqueous extract, ethanol-water extract and 30% ethanol extract all had antihypertensive effect on anesthetized animals. Potassium salts and alkaloids in ash have a diuretic effect. Alkaloid composition and water-soluble part of the rat intestinal motility inhibited. This effect is antagonistic to acetylcholine. In addition, crude drug extracts have inhibitory effects on the growth of Staphylococcus aureus and E. coli. Potassium nitrate contained in crude drug can be reduced into potassium nitrite in vivo, which can cause methemoglobin and produce asphyxiation. Apart from the above-mentioned effects, alkaloids also have a central stimulant effect on rats. A dose of 50 mg/kg may induce convulsions and 20 mg/kg, which may significantly reduce vitamin C content in the adrenal glands of rats and increase blood glucose and cholesterol. The plasma concentration of renal corticosteroids.


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