Regenerative medical scientists "plant" heart tissue on spinach leaves

Remember the ear that was cultivated with apples? Scientists have discovered that apple petals grow like ears, so they use the skeleton of apples to cultivate human ears.

再生医学科学家在菠菜叶上“种”出心脏组织

Nowadays, the scientists have opened their brains again. They use the spinach leaves to cultivate the heart. It is even bigger than the apple ears. This time, it actually brought the "blood vessels" directly!

再生医学科学家在菠菜叶上“种”出心脏组织

Image source: Worcester Polytechnic Institute

Scientists studying regenerative medicine have previously discovered that although animals and plant cells are different, their cellulose backbones are interlinked. Using the cellulose backbone of plant cells to support the growth of animal cells allows us to train Animal tissue that can be used for replacement.

Previously, scientists have used apple cellulose backbone to culture human cells, allowing humans to grow "ears." Now, Professor Glenn Gaudette and his colleagues from the Worcester Institute of Biomedical Engineering discovered The other two cross-border organizations are the spinach leaves and heart.

Spinach leaves have a rich network of veins, which is similar to the abundant capillaries in the heart. Although animal and plant tissues have very different principles for the transport of nutrients, their catheter network structures have striking similarities.

再生医学科学家在菠菜叶上“种”出心脏组织

Image source: hssszn

As a result, scientists removed the plant cells from the spinach leaves, leaving only the intact cellulose backbone. The process of removal is not complicated. It only needs to be soaked in a cleaning solution. After a while, the plant cells are washed away. The spinach used by scientists is not special and can be bought on the market.

After the decellularization process, the remaining cytoskeleton is transparent, and the rich vein network can still be seen intact. Scientists inoculated human cardiomyocytes into the cellulose skeleton of spinach, and transmitted nutrients through veins to simulate the living environment of human cardiomyocytes.

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