About 10% of breast cancers in China belong to familial breast cancer. Familial breast cancer refers to the aggregation of breast cancer in the family, that is, at least 2 or more of the first and second-degree relatives in the family have the original Breast cancer and / or ovarian cancer; or bilateral breast cancer patients. In 2013, the famous American movie star Angelina Jolie conducted a genetic test of BRCA1/2 due to her family history. The results showed that the BRCA1 gene mutation had a probability of breast cancer and ovarian cancer of 87% and 50%. She chose to surgically remove the bilateral breasts to reduce the risk of cancer by 87% to 5%.

Anti-cancer gene detection

The BRCA1/2 gene is the two most susceptible genes found to be most closely related to familial breast cancer. Huicheng gene research shows that women with BRCA1 and BRCA2 mutations are 10 times more likely to develop breast cancer than normal people, and BRCA1/2 gene can inhibit cancer. However, once these two genes have mutated, they have changed from tumor suppressor genes to oncogenes.

Anti-cancer gene detection

Huicheng Gene summarizes the lifetime risk of cancers associated with BRCA1 and BRCA2 mutations, showing mutations in the BRCA1 gene, with breast cancer and ovarian cancer at 50%-85% and 15%-45%, respectively, with BRCA2 mutations The risk of breast and ovarian cancer is 50%-85% and 10%-20%, respectively.

Which population should receive breast cancer BRCA1/2 gene testing?

If a member of the family meets any of the following conditions, it suggests that the family may have a high risk of breast cancer. It is recommended that breast cancer patients or high-risk individuals in this family receive BRCA1/2 gene testing:

Anti-cancer gene detection

Disinfection And Sterilization Equipment

Plasma Air Sterilizer,Plasma Air Sterilizing Machine ,Air Sterilization Purifier,Bio Plasma Air Sterilizers

Foshan Ja Suo Medical Device Co., LTD , https://www.jasuodental.com