Release date: 2017-06-02

It is understood that a research team at the Aikenhead Medical Discovery Center in St. Vincent Hospital, Melbourne, Australia, successfully tested its innovative “bio-pen”. This 3D bioprint pen filled with stem cell hydrogel inks allows doctors to easily print live cells onto injured muscles, bones, tendons and other tissues. In the test, it was used to repair the knee of a sheep.

The body of the device has a lightweight and ergonomic structure and is said to be made of medical plastic and titanium. Its titanium nozzle is capable of extruding bio-ink containing stem cells and a hydrogel made of gelatin and hyaluronic acid. After extrusion, a low power UV will cure the mixture.

In a recent test, the bio-ink contained on the pen consisted of stem cells of sick sheep and a biocompatible hydrogel material. Doctors say the hydrogel not only allows cells to be printed, but also allows cells to survive and replicate.

Successful testing on sheep has provided a positive signal for the future of this bioprinting technology, and the research team hopes that their equipment will soon be used to repair cartilage damage that is currently difficult to treat. The biggest beneficiaries of bio-pens may be young people and athletes because they can heal the injuries they suffer, preventing or at least delaying osteoarthritis, one of the most common chronic joint diseases.

The treatment of osteoarthritis has obviously cost a lot of money in the medical system, and the use of this preventive tool can significantly reduce medical expenses in this area. On the other hand, for the surgeon, the 3D bioprint pen is also a relatively simple and easy to use tool, which makes the corresponding surgery easier to implement.

The 3D bioprint pen, jointly developed by St. Vincent Hospital, the University of Melbourne and the University of Wollongong, is currently in the commercial stage, and we may see its application on the human body next year.

(Compiled from 3ders.org)

Source: Tiangongshe

Antipyretic & Pain-killer

Antipyretic:

Something that reduces fever or quells it.

There are 3 classes of antipyretic medications that are sold OTC (over-the-counter) without prescription:

Salicylates -- aspirin (acetylsalicylic acid), choline salicylate (Arthropan), magnesium salicylate (Arthriten), and sodium salicylate (Scot-Tussin Original);

Acetaminophen (Tylenol); and

Nonsteroidal anti-inflammatory drugs (NSAIDs) -- ibuprofen (Advil), naproxen (Naprosyn, Aleve), and ketoprofen.

From anti-, against + the Greek pyretos, fever from pyr, fire. The same root gives rise to pyrexia, a medical term for fever.

Antipyretic, from the Greek anti, against, and pyreticus, pertaining to fever, are substances that reduce fever. Antipyretics cause the hypothalamus to override a prostaglandin-induced increase in temperature. The body then works to lower the temperature, resulting in a reduction in fever.

Most antipyretic medications have other purposes. The most common antipyretics in the United States are ibuprofen and aspirin, which are used primarily as pain relievers. Non-steroidal anti-inflammatory drugs (NSAIDs) are antipyretic, anti-inflammatory, and pain relievers.

Pain-killer:

Painkiller is any member of the group of drugs used to achieve analgesia, relief from pain.

Analgesic drugs act in various ways on the peripheral and central nervous systems. They are distinct from anesthetics, which reversibly eliminate sensation. Analgesics include paracetamol (known in North America as acetaminophen or simply APAP), the non-steroidal anti-inflammatory drugs (NSAIDs) such as the salicylates, and opioid drugs such as morphine and oxycodone.

In choosing analgesics, the severity and response to other medication determines the choice of agent; the World Health Organization (WHO) pain ladder specifies mild analgesics as its first step.

Analgesic choice is also determined by the type of pain: For neuropathic pain, traditional analgesics are less effective, and there is often benefit from classes of drugs that are not normally considered analgesics, such as tricyclic antidepressants and anticonvulsants.

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