In recent decades, humans have made substantial progress in the fight against cancer. Since the 1990s, cancer mortality has fallen by 26%, and accordingly, cancer survival rates are continuing to rise. It is estimated that in the United States, the number of cancer survivors has increased from 3 million in 1971 to 15.5 million in January 2016. About 73% of cancer survival benefits are attributed to new drugs. In 1988-2000, advances in cancer treatment have saved 23 million years of life and added $1.9 trillion in wealth to society based on increased productivity, longevity and other factors. Since 1975, the chances of cancer patients surviving for 5 years or longer have increased by 41% in all cancers.

This tremendous advancement is largely due to advances in molecular and genomic research that reveal the unique complexity of cancer and change the understanding of cancer. Today, scientists have realized that no two cancers are exactly the same. Cancer is essentially complex and diverse, just like the genetic material of each of us, is unique. Each patient's cancer is influenced and driven by a variety of unique factors, a disease widely known as cancer, which is actually hundreds of different diseases. These advances have also expanded scientific understanding of how cancer occurs and how to develop drugs that target specific cancer types to provide patients with new and more effective treatments.

The American Association of Pharmaceutical Research and Manufacturers (PhRMA) recently released a report that due to unprecedented advances in science, as many as 1,120 new drugs and vaccines are currently in clinical use in the United States or are awaiting approval from the US FDA for the treatment of various types of cancer. Prevention includes leukemia (137 species), lymphoma (135 species), lung cancer (132 species), breast cancer (108 species), hematological malignancies (103 species), and brain tumors (90 species). A detailed list of drugs can be found in the Medicines in Development for Cancer 2018 Report.

PhRMA pointed out that in the not too distant past, chemotherapy and radiotherapy were the only way to treat cancer. Despite a decline in cancer mortality in the last 20 years and a fivefold increase in survival rates since the 1970s, there is still more work to be done.

Scientific advances are leading the biopharmaceutical industry to a new era of medicine. And immuno-oncology and individualized treatment are ushering in a new era of cancer understanding and treatment. Compared to traditional anticancer drugs, immunotherapies such as CAR-T and checkpoint inhibitors use the body's own immune system to identify and kill cancer cells. In the past 2017 alone, there were 47 new ones. Immuno Oncology drugs are added to the R&D pipeline.

PhRMA pointed out that the 1,120 drugs and vaccines under development represent a growing scientific understanding of cancer, bringing new hope to various patient groups across the entire cancer lineage, which will lead humans to overcome cancer. A great vision is moving forward steadily. (Source: Sina Pharmaceutical News Compilation / newborn)

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