Give you a 5 minute recording. How much information can you get from this recording? According to a recent study by the University of Wisconsin-Madison Westman Center and the Wisconsin Discovery Institute, a five-minute conversation is enough to determine whether a person is susceptible to genetic disease and related complications.

As early as this study in Scientific Reports, researchers used machine learning to analyze hundreds of voice records and accurately identify the vulnerable X chromosomes in the pre-mutation phase of an individual. Increase the risk of neurodegenerative diseases, infertility and other diseases. In addition, the offspring of the population carrying the chromosome are prone to X chromosome vulnerability syndrome.

The main features of X-chromosomal vulnerability syndrome are intellectual and physical disabilities, and millions of people around the world currently have X-chromosome mutations. As a participant in the study, Professor Marsha Mailick, Associate Dean of the University of Wisconsin Graduate School, said: "These pre-mutation conditions are still not effectively diagnosed, and people are generally unaware that their risk of illness has increased."

Diagnosing a pre-mutation X chromosome is a difficult task that is extremely time consuming and requires a lot of resources to make it expensive. “Our research team wants to develop a fast, economical, and effective screening method,” Mailick said. It was with this appeal that they developed a machine learning-artificial intelligence calculation program. This new type of robot can "train" with existing data and then analyze new information.

Kris Saha, an associate professor of biomedical engineering at the University of Wisconsin, said: "In the first place, we spent hours analyzing and annotating each record. With such a lot of work, it took less than a second to use them."

In a previous study, Mailick and colleagues have shown that systematic speech recording analysis can yield valuable information about families with pre-fragile X chromosomes. In 2012, a study led by Vice President of the University of Wisconsin, Jan Greenberg, analyzed five-minute mothers' conversations about their children's voice records with X-chromosomal vulnerability syndrome. Studies have shown that a warm, positive family atmosphere created by parents can reduce a child's behavioral problems.

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