Release date: 2007-10-10 The value of osteopontin in the risk stratification of patients with stable angina pectoris According to plasma OPN level, the optimal cut-off value of risk stratification in patients with stable angina pectoris is 403 ng/ml, which is a reliable biochemical indicator. Angina is the main symptom of coronary heart disease and is a group of syndromes caused by acute transient myocardial ischemia and hypoxia. In the third issue of the March issue of the Chinese Journal of Cardiovascular Research, a case study was conducted in which the study used a case-by-case study to determine plasma OPN levels in 39 patients with stable angina and to observe adverse cardiovascular events at 6 months. Sexual death, non-fatal myocardial infarction). The receiver operating characteristic curve (ROC curve) was used to determine the OPN level threshold, according to which the patient risk was stratified into high-risk group and low-risk group. To explore the boundary point of osteopontin (OPN) for risk stratification in patients with stable angina pectoris and its significance. Liu Peng, a cardiologist at the Department of Thoracic Surgery, Henan Province, showed that the optimal cut-off value for the risk stratification of plasma OPN levels was 403 ng/ml, with a sensitivity of 78.6% and a specificity of 90.9%. There were 13 cases (76.5%) with adverse cardiovascular events in the high-risk group, and 4 cases (23.5%) without events, and 5 cases (22.7%) and 17 cases (77.3%) in the low-risk group. The prognosis of the high-risk group was worse in the lower-risk group (76.5% and 22.7%, P=0.001; RR3.365, 95% CI 1.490-7.597). Therefore, it can be seen that the optimal cut-off value of risk stratification in patients with stable angina pectoris according to plasma OPN level is 403 ng/ml, which is a reliable biochemical indicator. ——Midi Medical Network
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The value of osteopontin in the risk stratification of patients with stable angina pectoris