Release date: 2009-12-03 Dongguan Anmeixuan Electronic Technology Co., Ltd , https://www.hyashine.com
According to the McGill University Health Center website, the first clinical trial of the new AIDS treatment method developed by the center's researchers was successful. The researchers say the therapy may be more effective and has a brighter future than the current popular cocktail therapy.
According to the report, the therapy was jointly developed by Dr. JP Rudy of the McGill University Health Center Institute and Dr. R. Sikale of the University of Montreal. As an immunotherapy, it can be tailored to different patients by vaccination. Guide the "immune system" against specific HIV in people living with HIV. In the first phase of the clinical trial, the researchers used the therapy in combination with antiretroviral drugs, and the results were published in the recent issue of Clinical Immunology. Phase II clinical trials are currently being conducted in eight different locations in Canada with the primary goal of testing the effectiveness of the therapy itself.
The new therapy uses dendritic cells as a vehicle. These cells are obtained from HIV-infected individuals and cultured in vitro. As the most powerful antigen-presenting cell known to date, dendritic cells present invading viral substances, enabling the rest of the body's immune system to recognize and attack invading viruses. "They are the 'great commanders' of the human immune response," Dr. Rudy explained. "With them, you can push the immune system and perform all of its functions at the same time." In clinical trials, dendritic cells are exposed to HIV RNA in a particular patient, and this exposure causes the cell to develop its defense against a particular strain. The modified cells, called AGS-004, will be injected again into the patient. Clinical trial results show that AGS-004 has almost no side effects, and the CD8-lymphocyte content in patients also increases significantly. CD8-lymphocytes are "attack" cells of the human immune system.
According to the report, Dr. Rudy hopes to develop a new AIDS treatment method to stimulate the body's immune system against HIV. This therapy requires less injection and produces a shorter duration of toxicity than antiretroviral therapy. Researchers believe that this new treatment may be more effective than the current antiretroviral "cocktail" therapy and has enormous room for development.
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New AIDS therapy is more effective than cocktail therapy