Smart chip enhances early screening technology for breast cancer

At present, breast cancer has become the biggest disease threatening women's health. The 4th China "Internet +" College Students Innovation and Entrepreneurship Competition was held in Xiamen University shortly before. After fierce competition, the team project "Renxin Technology - Microfluidic Chip Breast Cancer Early Screening Intelligent System" led by Professor Hu Bo of Xi'an University of Electronic Science and Technology of Life Science and Technology won the national silver award.

Smart new technology costs less and has higher accuracy

Microfluidic chip early breast cancer screening intelligent system named "Benechip", "bene" has a kind meaning, "chip" refers to the chip, together they are translated into "Renxin", which is also "Renxin Technology" The source of the name. Referring to the beginning, Dr. Yin Pengju, the team leader and the School of Life Science and Technology, said: "Our team is not only committed to making the best chips, but more importantly, using our technology to complete early breast cancer screening and solving many years of troubles. The problem."

Early breast cancer often does not have typical symptoms and signs, and it is not easy to attract attention. This also increases the difficulty of breast cancer examination and leads to increased patient mortality. Early diagnosis is a method of diagnosis and treatment for patients with early cancer, and early treatment can be found early. Most of the current early screening for breast cancer uses ultrasound, mammography, and nuclear magnetic resonance, but there are significant uncertainties in these traditional approaches. For example, ultrasound examination can not accurately and quickly screen tumor cells, and the traditional microfluidic chip has a complicated structure, and many places require manual operation. These technical defects not only greatly increase the difficulty of detection, but also cannot be applied in a wide range, and lack of practicality.

Tumor cells and ordinary blood cells are very different in size and structure. Renxin Science and Technology team is using this to achieve tumor cell screening, and developed an early screening system for breast cancer based on microfluidic chip technology. Benechip.

Benechip is less expensive, more accurate, and more popular than several other screening methods. The traditional microfluidic chip has a complicated structure and requires manual operation in many places. The Renxin Technology team made further innovations based on the traditional microfluidic chip technology. In order to reduce costs, the team decided to adopt 3D printing, which is convenient, quick and saves manpower and material resources. In terms of accuracy, they use a self-developed material to amplify the cellular information, enabling the chip to better identify the signal and improve the algorithm to improve the accuracy of the chip.

It is worth mentioning that Benechip can not only detect breast cancer, but also detect other cancers by investigating data from other tumor cells and modifying the chip.

Team diligence + multiple instructors polishing

There are so many excellent teams and projects. How does the Renxin team use their wisdom to impress investors on the main track of the country? In the roadshow process, in order to enable investors to fully understand their projects, under the guidance of entrepreneurial tutor Tan, they made a metaphor for chip design. Since the cross section of the chip is similar to the shape of the Dujiangyan River, the team decided to put a picture of Dujiangyan on the left side of the PPT, a chip image on the right side, a macroscopic view, a microscopic view, and then extend the macro Dujiangyan structure to the microscopic microfluidic chip, just right. Explain how the microfluidic chip works. Such wisdom and skill are displayed in every process of their game.

It is this kind of creativity and the hard work before each road show that their projects have successfully attracted investors and judges. Chen Zezhou, a team member and graduate student of the School of Life Science and Technology, said with emotion: "From the road show on stage to the revision of the lectures and PPTs in the audience, every step we take is backed by the support of the school and the leaders and teachers. Innovation The Entrepreneurship Institute has organized many trainings and coaches for us. In the past one year, the projects have been polished. Dozens of teachers have given us multi-dimensional guidance, including Professor Shi Guangming from the Institute of Artificial Intelligence, Professor Tian Jie from the School of Life Science and Technology, and Shanghai Alumni. Mr. Wang Yang, President of the Association, Mr. Yang Zhongjie, Co-founder of Mobike Bicycle, Mr. Zhang Wenbo, the person in charge of the 3rd 'Internet +' Gold Award Project, Mr. Zhu Wei from the Innovation and Entrepreneurship Institute, and Mr. Hu Bo, the project tutor, etc. Special thanks to all of them for this. The sweat of the second game, without them, there will be no Renxin team standing on the stage of the national finals."

Make unremitting efforts to save more women's lives

During the research process, the members and the responsible person disagreed. Finally, they decided to make two generations of products, each of which realized their own ideas, and then selected the better one. In the Renxin team, members respect each other and help each other, and always adhere to the spirit of teamwork.

As a Xidian university student who is at the forefront of the times, the Renxin team uses their projects to serve the society, and is committed to technology while not forgetting the original heart, truly protecting the health of women. When it comes to the future, Renxin team admits that it will further improve the quality of the chip and make unremitting efforts to save more women's lives.

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