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Pharmaceutical Raw Material Sarms Raw Powder Aicar Acadesine CAS 2627-69-2
1 . Quick Details:
Product Name:
Aicar
CAS:
2627-69-2
MF:
C9H14N4O5
MW:
258.23
Appearance:
White Powder
Usage
Aicar is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia.
2 . Product Description:
Â
Aicar is a peptide whose technical name is 5-Aminoimidazole-4-carboxamide ribonucleotide. It can also be known as AICA ribonucleotide, ZMP, or Acadesine. It is an intermediate contained in the generation of inosine monophosphate. It primarily functions as an AMP-activated protein kinase agonist, meaning that it has the ability to promote the operation of nutrient stores for energy production. It has a molecular mass of 338.211, and it has a molecular formula of C9H15N4O8P.
Aicar is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis (Hardie and Carling).
Aicar can play a hand in boosting these processes because it contains the ability to penetrate cardiac cells and block the production of enzymes tied to regulating glucose intake and energy expulsion. With these regulatory enzymes inhibited, the affected cells can in turn boost the amount of glucose that can be received, and it can also increase its level of energy conversion. Additionally, the peptide's presence has been determined to aid in lowering programmed cell death, a process that is also known as apoptosis.
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3 . Product Application:
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Aicar (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR& alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes.
Studies demonstrate that AICAR can mimic the activity of insulins (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase).
The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.
Our Advantage:
1.We have stock so we can delivery quickly at the very day when receive the payment.
2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order.
3.High quality guarenteed, once any problem is found, the package would be reshipped for you
4.Shipping by express (FedEx,UPS,DHL,EMS TNT HKEMS), by air . The most professional forwarder would be recommanded for you.
5 . Warm aftersale service for you 24/7 . Any of your question would be solved for the first as soon as possible . Adhering to the principle of customer first conviction . we will provide the best and the most sincere services as possible as we can.
Delivery
1. Sent out in 24hours once payment comfirm.
2. Professional agent make sure our ship fastly and safety
3.Offer your tracking number to you once we get it ,in order to facilitate you track the express
FAQ
1.How about parcel delivery success rate ?
Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%. As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.
2.What is The Minimum And Maximum Amount Of Steroid Powder IÂ Can Order At One Time?
Normally, our min.order quantity is 10g,please feel free to contact us about the specific order.
We suggest the net weight of each package should be less than 3.5kg. But if your order quantity is more than 3.5 kg, we will split the goods into several packages and then send you separately.
3.Do You Ship Over The Weekend?
We use EMS,TNT,FEDEX,DHL four kinds of couriers. EMS don't collected parcels over the weekend. The packages can be shipped out normally before 12:00 a.m in Beijing time if you choose to ship by TNT or FedEx.
Pharmaceutical Raw Material Sarms Raw Powder Aicar Acadesine CAS 2627-69-2
1 . Quick Details:
Product Name:
Aicar
CAS:
2627-69-2
MF:
C9H14N4O5
MW:
258.23
Appearance:
White Powder
Usage
Aicar is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia.
2 . Product Description:
Â
Aicar is a peptide whose technical name is 5-Aminoimidazole-4-carboxamide ribonucleotide. It can also be known as AICA ribonucleotide, ZMP, or Acadesine. It is an intermediate contained in the generation of inosine monophosphate. It primarily functions as an AMP-activated protein kinase agonist, meaning that it has the ability to promote the operation of nutrient stores for energy production. It has a molecular mass of 338.211, and it has a molecular formula of C9H15N4O8P.
Aicar is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis (Hardie and Carling).
Aicar can play a hand in boosting these processes because it contains the ability to penetrate cardiac cells and block the production of enzymes tied to regulating glucose intake and energy expulsion. With these regulatory enzymes inhibited, the affected cells can in turn boost the amount of glucose that can be received, and it can also increase its level of energy conversion. Additionally, the peptide's presence has been determined to aid in lowering programmed cell death, a process that is also known as apoptosis.
Â
Â
3 . Product Application:
Â
Aicar (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR& alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes.
Studies demonstrate that AICAR can mimic the activity of insulins (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase).
The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.
Our Advantage:
1.We have stock so we can delivery quickly at the very day when receive the payment.
2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order.
3.High quality guarenteed, once any problem is found, the package would be reshipped for you
4.Shipping by express (FedEx,UPS,DHL,EMS TNT HKEMS), by air . The most professional forwarder would be recommanded for you.
5 . Warm aftersale service for you 24/7 . Any of your question would be solved for the first as soon as possible . Adhering to the principle of customer first conviction . we will provide the best and the most sincere services as possible as we can.
Delivery
1. Sent out in 24hours once payment comfirm.
2. Professional agent make sure our ship fastly and safety
3.Offer your tracking number to you once we get it ,in order to facilitate you track the express
FAQ
1.How about parcel delivery success rate ?
Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%. As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.
2.What is The Minimum And Maximum Amount Of Steroid Powder IÂ Can Order At One Time?
Normally, our min.order quantity is 10g,please feel free to contact us about the specific order.
We suggest the net weight of each package should be less than 3.5kg. But if your order quantity is more than 3.5 kg, we will split the goods into several packages and then send you separately.
3.Do You Ship Over The Weekend?
We use EMS,TNT,FEDEX,DHL four kinds of couriers. EMS don't collected parcels over the weekend. The packages can be shipped out normally before 12:00 a.m in Beijing time if you choose to ship by TNT or FedEx.
Pharmaceutical Raw Material Sarms Raw Powder Aicar Acadesine CAS 2627-69-2
MOQ: 10g
CAS: 2627-69-2
Mf: C9h14n4o5
MW: 258.23
Trademark: DMK
Transport Package: Foil Bag
Specification: API
Origin: China
HS Code: 29061310
MOQ: 10g
CAS: 2627-69-2
Mf: C9h14n4o5
MW: 258.23
Trademark: DMK
Transport Package: Foil Bag
Specification: API
Origin: China
HS Code: 29061310