Pig streptococcosis is an infectious disease caused by pathogenic streptococci. The main features of this disease are: sepsis, meningoencephalitis, arthritis, endocarditis, lymphatic abscess.

First, epidemiological characteristics

The disease can occur all year round, but it occurs frequently in summer and autumn. A variety of animals, poultry and humans are susceptible to this disease, so it is a common disease for humans and animals. The susceptibility of suckling piglets and weaners is stronger than that of pigs, and it is more frequent. Followed by the middle pig, pigs rarely ill. Pregnant sows occasionally see the disease. The bacteria are infected through the digestive tract, respiratory tract, wounds and the umbilical cord of the piglet. It has been reported abroad that flies can also carry S. suis type II to spread the disease. Acute sick pigs have high morbidity and mortality rates. The disease is endemic and has a violent occurrence in the new epidemic area.

Second, the symptoms

1, sepsis type. In the early days, the most acute sick pig died suddenly and showed no symptoms. The acute sick pig is depressed, the appetite is abolished, and the body temperature is as high as 41-42 °C. Difficulty breathing and rapid heartbeat. Nasal discharge of mucous or purulent nasal fluid. The conjunctiva is flushed and weeping. There are purple spots on the tip of the ear, the lower part of the limbs and the lower abdomen. Constipation, dry feces. Walk and walk, hi lying. The course of disease is 1-3 days. Weaned piglets are mostly of this type.

2, meningeal encephalitis type. In the early stage, the body temperature is as high as 42 ° C, antifeeding, constipation. Nasal discharge of serous or tumbling nasal fluid. There are movement disorders, turning circles, molars, supine, hind limb paralysis, swimming strokes, coma and other neurological symptoms. Some pigs developed joint swelling and lameness, with a course of 1-2 days. Feeding piglets and weaned piglets are frequent.

3, arthritis type. More from the first two types. The joints of one or several limbs are swollen, painful, lame, and serious sick pigs cannot stand. The course of disease is 1-2 days.

4, lymph node abscess type. More common in the lymph nodes, followed by swollen throat and neck lymph nodes, hot, hot, eating, chewing, swallowing and breathing difficulties. The center of the swelling becomes soft, purulent, ruptured, and the milky white or yellow-brown pus flows out. The granulation is proliferated after the pus is discharged, and it can heal itself. The course of disease is 3-5 days.

In short, sepsis type and meningoencephalitis type are the most acute and acute, and joint type and lymph node abscess type, endocarditis, metritis, mastitis, dermatitis and local abscess are all chronic.

Third, necropsy

1, sepsis type: mainly hemorrhagic sepsis lesions and serositis. It can be seen that there are purple plaques on the skin of the ears, the abdomen, and the extremities. Mucosa, serosa, subcutaneous hemorrhage. Nasal mucosa congestion, bleeding, purple-red. Throat, tracheal mucosal bleeding, and a lot of foam. The lungs are congested and swollen. Whole body lymph node congestion, hemorrhage, swelling, necrosis of the face, suppuration. The cerebral cavity, abdominal cavity and pericardial effusion, turbid, containing flocculent cellulose attached to the organ and adhere to the organ. Splenomegaly, poor blood clotting.

2, meningeal encephalitis type. Meningeal congestion, hemorrhage, increased cerebrospinal fluid opacity, leukocytosis. Parenchymal encephalitis lesions can be seen in the brain parenchyma. Swelling around the joints, congestion, turbid fluid in the joint capsule. The brain slice has a large bleeding point at the tip of the needle. And have sepsis type lesions.

3, arthritis type. Swelling around the joints, congestion, turbid fluid in the joint capsule, yellow gum-like or fibrinous purulent exudate. The synovial surface of the joint is rough, and there are multiple suppurative foci in the tissue around the joint. The above three types are mixed in excess.

Fourth, diagnosis

(1) According to clinical symptoms, especially sepsis, elevated body temperature, meningoencephalitis, arthritis and lymph node abscess, can be initially diagnosed. However, it is best to have a pathogen test.

(2) taking the blood of the sick pig, liver, spleen, joint cyst fluid, cerebrospinal fluid and suppurative foci, etc., contact or smear, Gram stain microscopic examination, visible single, paired, short-chain or long-chain purple cocci. Bacterial isolation and culture can also be carried out under conditions.

(3) Take the diseased material or isolate the culture, inoculate the mice subcutaneously or intraperitoneally, and die at 18-72 hours, showing a change in sepsis. A large number of streptococci can be seen when taking the disease material, smear, staining and microscopic examination.

(4) Serological diagnosis. Fluorescent antibodies, latex agglutination test, SPA synergistic agglutination test can be used to check the disease, and the effect is good.

(5) Differential diagnosis. The disease should be diagnosed differently from swine fever, pig erysipelas, swine plague, and piglet paratyphoid.

Fifth, prevention

1. Strengthen feeding management, improve environmental sanitation, and do a good job of disinfection. Eliminate the pathogenic factors and find that traumatic pigs should be treated promptly. Castration, injection, and umbilical cord should be strictly disinfected. The pig floor, utensils, work clothes, etc. should be disinfected regularly. It is necessary to eliminate flies and the like in the pig house to control the occurrence of this disease.

2, immune prevention. Streptococcus suis hydrogenated aluminum bacterin vaccine, regardless of the size of the pigs, muscle or subcutaneous injection of 5 ml (concentrated seedlings 3 ml), 21 days after injection to produce immunity, the immune period is about 6 months. Streptococci attenuated vaccine, diluted with 1 ml of 20% aluminum gel in normal saline, and then weaned to adult pigs after weaning, all muscle or subcutaneous injection of 1 ml. The seedling can also be taken orally, but the amount is doubled.

3. Treatment. For septic and meningoencephalitis, antibiotics and sulfonamides can be used. For example, penicillin is 40-100 million international units per head, intramuscularly, 2-4 times a day. Gentamicin is 1-2 mg per kilogram of body weight, intramuscularly, 2 times a day. Sodium sulfadiazine injection, 0.07 g per kg body weight, intramuscularly. Ethyl ciprofloxacin 2.5-10 mg per kilogram of body weight, once every 12 hours, for 3 days, the effect is obvious. The lymph node abscess type was cut with a knife, the pus was drained, rinsed with hydrogen peroxide, and then coated with iodine.

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